Medicines Control Authority of Zimbabwe

Public Clinical Trials Registry

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Page 2 of 2, showing 13 record(s) out of 33 total

Protocol No Public Title Scientific Title Date Submitted Date approved
CT268/2023 OCIS Placebo Ring Study MATRIX-003 Trial to Assess Acceptability and Safety of Two Placebo Intravaginal Ring (IVR) Designs 25-10-2023 11:27 30-10-2023 View  
CT269/2023 A Multicenter, Adaptive, Randomized, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections (STRIVE) Version 1.0 Dated 11 November 2022 A Multicenter, Adaptive, Randomized, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections (STRIVE) Trial 1: Appendix E-1: Shionogi Protease Inhibitor (S-217622) Trial 13-11-2023 16:29 05-09-2024 View  
CT272/2024 Pharmacokinetic study of a novel DTG/FTC/TAF dose ratio for children Pharmacokinetic study of an optimized dose ratio of dolutegravir/emtricitabine/tenofovir alafenamide fumarate: expediting a UNIVERSAL first line regimen for all children living with HIV in Africa 05-01-2024 09:54 07-11-2024 View  
CT273/2024 STRIVE IMMUNUNE MODULATION TRIAL A Multicentre, Adaptive, Randomised, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized patients with Respiratory Infections (STRIVE) Version 1.0, 11 November 2022 INSIGHT Protocol Number: 018 / ACTIV 22-01-2024 10:28 26-02-2024 View  
CT275/2024 GSK_ViiV_221163 Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition. 13-03-2024 09:24 13-07-2025 View  
CT280/2024 The Friendship Bench Plus trial (FB+Trial) Combining antidepressants with psychological therapy to improve depression outcome in Zimbabwe - the Friendship Bench Plus trial (FB+Trial) 19-07-2024 18:14 01-08-2025 View  
CT278/2024 An open-label, single-arm study to provide continued access to study drug to participants who have completed pediatric clinical studies involving Gilead HIV treatments: GS-US-380-6684 An open-label, single-arm study to provide continued access to study drug to participants who have completed pediatric clinical studies involving Gilead HIV treatments 05-06-2024 14:59 01-07-2025 View  
CT283/2024 OPTImising Metabolic management on Integrase based ART (OPTIMAR) A Phase III/IV factorial randomised double-blind trial to compare the addition of dapagliflozin versus placebo, and rosuvastatin/ezetimibe versus pitavastatin, in patients with HIV on integrase strand transfer inhibitor-based antiretroviral therapy with e 28-10-2024 14:30 14-05-2025 View  
CT281/2024 GRAdHIVNE1 Vaccine Trial A Phase 1 Randomized Double Blinded Placebo Controlled, Dose Ranging Trial, of a Gorilla Adenovirus Vectored Networked Epitopes Vaccine (GRAdHIVNE1 Vaccine), Administered to Healthy Adults Living without HIV and Living with HIV, in Southern Africa 16-10-2024 13:42 03-07-2025 View  
CT288/2025 SMILE-TB Shortened RegiMen for Drug-susceptIbLE TB in Children (SMILE-TB) Version 1.0 dated 21 February 2024 02-07-2025 10:14 10-07-2025 View  
CT286/2025 ACRNMNK02-301 A Phase 3, randomized, double-blind, placebo-controlled trial to evaluate the effect of Bifidobacterium longum subsp. infantis DSM33361(Bifin02) administered together with Lacticaseibacillus rhamnosus GG DSM33156 (LGG®) versus placebo on weight gain in un 12-05-2025 15:06 15-10-2025 View  
CT289/2025 RADIO-TB Optimal Treatment Duration of Radiographically Apparent, Bacteriologically Unconfirmed TB Identified Through Active Case Finding 06-10-2025 13:46 13-03-2026 View  
CT290/2026 IMPACT-AYP; Implementation of Multi-method PrEP in Adolescents & Young People Integration of a PrEP choice package with long-acting HIV prevention strategies into HIV/AIDS & STI prevention and care package for adolescents and young people accessing services at the Mbare Adolescent Sexual Reproductive Health (ASRH) Centre, Zimbabwe 24-02-2026 15:14 05-06-2026 View