Public Clinical Trials Registry
Page 1 of 2, showing 20 record(s) out of 24 total
| Protocol No | Public Title | Scientific Title | Date Submitted | Date approved | |
|---|---|---|---|---|---|
| CT199/2020 | AMC 102 | A Randomized Phase II Trial of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Paclitaxel and Carboplatin in HIV-Positive Women with Locally Advanced Cervical Cancer (LACC) (Version 3.0 09JUL2019) | 01-07-2020 13:32 | 03-04-2021 | View |
| CT269/2023 | A Multicenter, Adaptive, Randomized, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections (STRIVE) Version 1.0 Dated 11 November 2022 | A Multicenter, Adaptive, Randomized, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections (STRIVE) Trial 1: Appendix E-1: Shionogi Protease Inhibitor (S-217622) Trial | 13-11-2023 16:29 | 05-09-2024 | View |
| CT273/2024 | STRIVE IMMUNUNE MODULATION TRIAL | A Multicentre, Adaptive, Randomised, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized patients with Respiratory Infections (STRIVE) Version 1.0, 11 November 2022 INSIGHT Protocol Number: 018 / ACTIV | 22-01-2024 10:28 | 26-02-2024 | View |
| CT227/2021 | HVTN 140/HPTN 101 | A phase 1 dose-escalation clinical trial to evaluate the safety, tolerability, and pharmacokinetics of PGDM1400LS alone and in combination with VRC07-523LS and PGT121.414.LS in healthy, HIV-uninfected adult participants | 01-10-2021 17:29 | 05-05-2022 | View |
| CT281/2024 | GRAdHIVNE1 Vaccine Trial | A Phase 1 Randomized Double Blinded Placebo Controlled, Dose Ranging Trial, of a Gorilla Adenovirus Vectored Networked Epitopes Vaccine (GRAdHIVNE1 Vaccine), Administered to Healthy Adults Living without HIV and Living with HIV, in Southern Africa | 16-10-2024 13:42 | 03-07-2025 | View |
| CT219/2021 | IMPOWER 022 | A Phase 3, Randomized, Active-Controlled, Double-blind Clinical Study to Evaluate the Efficacy and Safety of Oral Islatravir Once-Monthly as Preexposure Prophylaxis in Cisgender Women at High Risk for HIV-1 Infection | 30-06-2021 17:00 | 31-05-2021 | View |
| CT221/2021 | A Phase I/II Study to Evaluate the Safety, Reactogenicity and Immunogenicity of RBD SARS-CoV-2 HBsAg VLP Vaccine in Healthy Adults | 22-06-2021 20:10 | 10-11-2021 | View | |
| CT230/2022 | ENGAGE | A Phase II Acceptability Study of Oral emtricitabine/tenofovir alafenamide (F/TAF) vs emtricitabine/tenofovir disoproxil fumarate (F/TDF) for the Prevention of HIV Acquisition in Adolescent Girls and Young Women (AGYW) | 23-02-2022 14:53 | 15-03-2022 | View |
| CT241/2022 | IMAGINE-TBM -A5384 | A Phase II, Randomized, Open-Label Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents with Tuberculous Meningitis: Improve | 25-08-2022 16:12 | 12-12-2023 | View |
| CT228/2021 | BREATHER+ | A randomized open-label 2-arm, 96-week trial evaluating the efficacy, safety and acceptability of short cycle (five days on, two days off) dolutegravir/tenofovir-based triple antiretroviral therapy (ART) compared to daily dolutegravir/tenofovir-based trip | 01-11-2021 19:32 | 02-04-2022 | View |
| CT225/2021 | R34 DPP Clinical Study-A crossover acceptability study assessing a DPP capsule for HIV and pregnancy prevention | A randomized, crossover study to evaluate the acceptability of an over-encapsulated dual prevention pill (DPP capsule) containing pre-exposure prophylaxis (PrEP) and a combined oral contraceptive (COC) pill versus two separate tablets (PrEP and COC) among | 14-09-2021 16:00 | 05-05-2022 | View |
| CT262/2023 | An adaptive multi-arm trial to improve clinical outcomes among children recovering from complicated severe acute malnutrition (Co-SAM) | 30-06-2023 18:59 | 01-02-2024 | View | |
| CT261/2023 | The CATALYST Study | Catalyzing access to new prevention products to stop HIV | 23-06-2023 09:39 | 12-12-2023 | View |
| CT232/2022 | CCNO17 | Clinical Evaluation of Daily Application of Nestorone® (NES) and Testosterone (T) Combination Gel for Male Contraception | 27-02-2022 20:13 | 21-06-2022 | View |
| CT220/2021 | COMBI | Cotrimoxazole for Mothers to improve birth weight in infants | 09-07-2021 10:48 | 10-11-2021 | View |
| CT243/2022 | ZIMCoVVAR | COVID 19 vaccine effectiveness and SARS CoV-2 variants in Zimbabwe:Test negative case control study, Genetic Sequencing and Serology | 12-09-2022 14:12 | 20-10-2022 | View |
| CT183/2019 | CT183/2019 MTN-042 | CT183/2019 MTN-042: A Phase 3b, Randomized, Open Label, Safety Trial of Dapivirine Vaginal Ring and Oral TRUVADA Use in Pregnancy | 12-11-2019 07:24 | 01-06-2020 | View |
| CT190/2020 | Thermal Ablation Study | Evaluation of the acceptability, safety and effectiveness of thermal ablation in the prevention of cervical neoplasia in Zimbabwe | 27-03-2020 09:07 | 15-02-2021 | View |
| CT247/2022 | LATA | Long-Acting Treatment in Adolescents (LATA): A randomised open-label 2-arm 96-week trial in virologically suppressed HIV-1-positive adolescents aged 12-19 years of age in Sub-Saharan Africa | 14-10-2022 14:29 | 16-12-2022 | View |
| CT268/2023 | OCIS Placebo Ring Study | MATRIX-003 Trial to Assess Acceptability and Safety of Two Placebo Intravaginal Ring (IVR) Designs | 25-10-2023 11:27 | 30-10-2023 | View |