Public Clinical Trials Registry
Page 1 of 2, showing 20 record(s) out of 35 total
| Protocol No | Public Title | Scientific Title | Date Submitted | Date approved | |
|---|---|---|---|---|---|
| CT295/2026 | HVTN 141/HPTN 105 | A phase 1 open label clinical trial to evaluate the safety, pharmacokinetics, and in vitro neutralization of ePGT121v1-LS, PGDM1400LS, VRC07-523LS, and PGT121.414.LS administered in multiple doses and routes to adult participants without HIV-1 | 26-06-2026 11:45 | 18-09-2026 | View |
| CT292/2026 | HPTN 104 | A multisite, open-label, randomized crossover study comparing adherence to a single daily dual prevention pill (DPP) versus FTC/TDF and Combined Oral Contraception separate pill dosing (2PR), given for pre-exposure prophylaxis and pregnancy prevention in | 01-04-2026 11:13 | 08-04-2026 | View |
| CT290/2026 | IMPACT-AYP; Implementation of Multi-method PrEP in Adolescents & Young People | Integration of a PrEP choice package with long-acting HIV prevention strategies into HIV/AIDS & STI prevention and care package for adolescents and young people accessing services at the Mbare Adolescent Sexual Reproductive Health (ASRH) Centre, Zimbabwe | 24-02-2026 15:14 | 05-06-2026 | View |
| CT289/2025 | RADIO-TB | Optimal Treatment Duration of Radiographically Apparent, Bacteriologically Unconfirmed TB Identified Through Active Case Finding | 06-10-2025 13:46 | 13-03-2026 | View |
| CT288/2025 | SMILE-TB | Shortened RegiMen for Drug-susceptIbLE TB in Children (SMILE-TB) Version 1.0 dated 21 February 2024 | 02-07-2025 10:14 | 10-07-2025 | View |
| CT286/2025 | ACRNMNK02-301 | A Phase 3, randomized, double-blind, placebo-controlled trial to evaluate the effect of Bifidobacterium longum subsp. infantis DSM33361(Bifin02) administered together with Lacticaseibacillus rhamnosus GG DSM33156 (LGG®) versus placebo on weight gain in un | 12-05-2025 15:06 | 15-10-2025 | View |
| CT283/2024 | OPTImising Metabolic management on Integrase based ART (OPTIMAR) | A Phase III/IV factorial randomised double-blind trial to compare the addition of dapagliflozin versus placebo, and rosuvastatin/ezetimibe versus pitavastatin, in patients with HIV on integrase strand transfer inhibitor-based antiretroviral therapy with e | 28-10-2024 14:30 | 14-05-2025 | View |
| CT281/2024 | GRAdHIVNE1 Vaccine Trial | A Phase 1 Randomized Double Blinded Placebo Controlled, Dose Ranging Trial, of a Gorilla Adenovirus Vectored Networked Epitopes Vaccine (GRAdHIVNE1 Vaccine), Administered to Healthy Adults Living without HIV and Living with HIV, in Southern Africa | 16-10-2024 13:42 | 03-07-2025 | View |
| CT280/2024 | The Friendship Bench Plus trial (FB+Trial) | Combining antidepressants with psychological therapy to improve depression outcome in Zimbabwe - the Friendship Bench Plus trial (FB+Trial) | 19-07-2024 18:14 | 01-08-2025 | View |
| CT278/2024 | An open-label, single-arm study to provide continued access to study drug to participants who have completed pediatric clinical studies involving Gilead HIV treatments: GS-US-380-6684 | An open-label, single-arm study to provide continued access to study drug to participants who have completed pediatric clinical studies involving Gilead HIV treatments | 05-06-2024 14:59 | 01-07-2025 | View |
| CT275/2024 | GSK_ViiV_221163 | Long-Term Follow-Up of CAB LA for Participants in HPTN 083 and HPTN 084 CAB PrEP Studies at Risk of HIV Acquisition. | 13-03-2024 09:24 | 13-07-2025 | View |
| CT273/2024 | STRIVE IMMUNUNE MODULATION TRIAL | A Multicentre, Adaptive, Randomised, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized patients with Respiratory Infections (STRIVE) Version 1.0, 11 November 2022 INSIGHT Protocol Number: 018 / ACTIV | 22-01-2024 10:28 | 26-02-2024 | View |
| CT272/2024 | Pharmacokinetic study of a novel DTG/FTC/TAF dose ratio for children | Pharmacokinetic study of an optimized dose ratio of dolutegravir/emtricitabine/tenofovir alafenamide fumarate: expediting a UNIVERSAL first line regimen for all children living with HIV in Africa | 05-01-2024 09:54 | 07-11-2024 | View |
| CT269/2023 | A Multicenter, Adaptive, Randomized, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections (STRIVE) Version 1.0 Dated 11 November 2022 | A Multicenter, Adaptive, Randomized, Controlled Trial Platform to Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections (STRIVE) Trial 1: Appendix E-1: Shionogi Protease Inhibitor (S-217622) Trial | 13-11-2023 16:29 | 05-09-2024 | View |
| CT268/2023 | OCIS Placebo Ring Study | MATRIX-003 Trial to Assess Acceptability and Safety of Two Placebo Intravaginal Ring (IVR) Designs | 25-10-2023 11:27 | 30-10-2023 | View |
| CT262/2023 | An adaptive multi-arm trial to improve clinical outcomes among children recovering from complicated severe acute malnutrition (Co-SAM) | 30-06-2023 18:59 | 01-02-2024 | View | |
| CT261/2023 | The CATALYST Study | Catalyzing access to new prevention products to stop HIV | 23-06-2023 09:39 | 12-12-2023 | View |
| CT258/2023 | Annovera Study | Pilot project to assess acceptability, uptake and continuation of Annovera® Contraceptive vaginal ring over 1 year (13 menstrual cycles) of use among adolescent girls and young women 16-24 years old seeking family planning services in two Mbare clinic | 14-03-2023 15:01 | 01-08-2024 | View |
| CT247/2022 | LATA | Long-Acting Treatment in Adolescents (LATA): A randomised open-label 2-arm 96-week trial in virologically suppressed HIV-1-positive adolescents aged 12-19 years of age in Sub-Saharan Africa | 14-10-2022 14:29 | 16-12-2022 | View |
| CT246/2022 | O-PrEP | Optimizing PrEP regimens for pregnant women in sub-Saharan Africa | 22-09-2022 09:55 | 12-12-2023 | View |